Molecular Ecology Phylogeographic differentiation in the mitochondrial control region in the koala, Phascolarctos cinereus (Goldfuss 1817) Log in to Wiley Online LibraryChange PasswordCongrats!Create a new accountForgot your password?Request Username
b.houlden@unsw.edu.aub.houlden@unsw.edu.auLearn more.Volume8, Issue6
- Skip to Article Content
- Skip to Article Information
This Journal
Anywhere
The full text of this article hosted at iucr.org is unavailable due to technical difficulties.
Molecular Ecology
Volume 8, Issue 6
Phylogeographic differentiation in the mitochondrial control region in the koala, Phascolarctos cinereus (Goldfuss 1817)
First published: 04 January 2002
https://doi.org/10.1046/j.1365-294x.1999.00656.x
Cited by: 44
Abstract
The koala, Phascolarctos cinereus, is a geographically widespread species endemic to Australia, with three currently recognized subspecies: P.c. adustus, P.c. cinereus, and P.c. victor. Intraspecific variation in the mitochondrial DNA (mtDNA) control region was examined in over 200 animals from 16 representative populations throughout the species’ range. Eighteen different haplotypes were defined in the ≈ 860 bp mtDNA control region, as determined by heteroduplex analysis/temperature gradient gel electrophoresis (HDA/TGGE). Any single population typically possessed only one or two haplotypes yielding an average within‐population haplotypic diversity of 0.180 ± 0.003, and nucleotide diversity of 0.16%. Overall, mtDNA control region sequence diversity between populations averaged 0.67%, and ranged from 0% to 1.56%. Nucleotide divergence between populations averaged 0.51%, and ranged from 0% to 1.53%. Neighbour‐joining methods revealed limited phylogenetic distinction between geographically distant populations of koalas, and tentative support for a single evolutionarily significant unit (ESU). This is consistent with previous suggestions that the morphological differences formalized by subspecific taxonomy may be interpreted as clinal variation. Significant differentiation in mtDNA‐haplotype frequencies between localities suggested that little gene flow currently exists among populations. When combined with microsatellite analysis, which has revealed substantial differentiation among koala populations, we conclude that the appropriate short‐term management unit (MU) for koalas is the local population.
Citing Literature
Number of times cited according to CrossRef: 44
Faye
Wedrowicz, Jennifer Mosse, Wendy
Wright and Fiona E. Hogan,
Genetic structure and diversity of the koala population in South Gippsland,
Victoria: a remnant population of high conservation significance,
Conservation Genetics,
10.1007/s10592-018-1049-8,
19, 3,
(713-728), (2018).Crossref
Litticia
M. Bryant and Matt N. Krosch,
Lines in the land: a review of evidence for eastern Australia's major biogeographical
barriers to closed forest taxa, Biological
Journal of the Linnean Society, 119, 2,
(238-264), (2016).Wiley Online Library
Faye
Wedrowicz, Tom Saxton, Jennifer
Mosse, Wendy Wright and Fiona
E. Hogan, A non-invasive tool for assessing pathogen prevalence
in koala (Phascolarctos cinereus) populations: detection of Chlamydia pecorum and
koala retrovirus (KoRV) DNA in genetic material sourced from scats,
Conservation Genetics Resources, 8,
4, (511), (2016).Crossref
Robert
M. Timm, Valter Weijola, Ken
P. Aplin, Stephen C. Donnellan, Tim F. Flannery, Vicki
Thomson and Ronald H. Pine,
A new species ofRattus(Rodentia: Muridae) from Manus Island, Papua New Guinea, Journal of Mammalogy, 97,
3, (861), (2016).Crossref
Christina
T. Ruiz-Rodriguez, Yasuko Ishida, Neil D. Murray, Stephen
J. O’Brien, Jennifer A. M. Graves, Alex D. Greenwood and Alfred
L. Roca, Koalas (Phascolarctos cinereus) From Queensland Are Genetically
Distinct From 2 Populations in Victoria, Journal of Heredity, 107, 7,
(573), (2016).Crossref
Shannon
R. Kjeldsen, Kyall R. Zenger, Kellie Leigh, William
Ellis, Jenifer Tobey, David
Phalen, Alistair Melzer, Sean
FitzGibbon and Herman W. Raadsma,
Genome-wide SNP loci reveal novel insights into koala (Phascolarctos cinereus)
population variability across its range, Conservation Genetics, 10.1007/s10592-015-0784-3, 17, 2,
(337-353), (2015).Crossref
S.
Dennison, G. J. Frankham, L.
E. Neaves, C. Flanagan, S.
FitzGibbon, M. D. B. Eldridge and R. N. Johnson, Population genetics
of the koala (Phascolarctos cinereus) in north-eastern New South Wales and south-eastern
Queensland, Australian
Journal of Zoology, 64, 6,
(402), (2016).Crossref
Linda
E. Neaves, Greta J. Frankham, Siobhan Dennison, Sean
FitzGibbon, Cheyne Flannagan, Amber Gillett, Emily
Hynes, Kathrine Handasyde, Kristofer
M. Helgen, Kyriakos Tsangaras, Alex D. Greenwood, Mark
D. B. Eldridge, Rebecca N. Johnson and Sam C Banks, Phylogeography of the
Koala, (Phascolarctos cinereus), and Harmonising Data to Inform Conservation, PLOS ONE,
11, 9,
(e0162207), (2016).Crossref
Natalie
J. Briscoe, Andrew Krockenberger, Kathrine A. Handasyde and Michael
R. Kearney, Bergmann meets Scholander: geographical variation
in body size and insulation in the koala is related to climate,
Journal of Biogeography,
42, 4,
(791-802), (2014).Wiley Online Library
Yasuko
Ishida, Kai Zhao, Alex
D. Greenwood and Alfred L. Roca,
Proliferation of Endogenous Retroviruses in the Early Stages of a Host Germ
Line Invasion, Molecular
Biology and Evolution, 10.1093/molbev/msu275, 32,
1, (109-120), (2014).Crossref
Jian
Cui, Greta J. Frankham, Rebecca
N. Johnson, Adam Polkinghorne, Peter Timms, Denis
O’Meally, Yuanyuan Cheng, Katherine
Belov and Michelle L. Baker,
SNP Marker Discovery in Koala TLR Genes, PLOS ONE, 10, 3,
(e0121068), (2015).Crossref
Karen
H. Black, Julien Louys and Gilbert
J. Price, Understanding morphological variation in the extant
koala as a framework for identification of species boundaries in extinct koalas (Phascolarctidae;
Marsupialia), Journal
of Systematic Palaeontology, 12, 2,
(237), (2014).Crossref
Jennifer
M. Seddon, Kristen E. Lee, Stephen
D. Johnston, Vere N. Nicolson, Michael Pyne, Frank
N. Carrick and William A. H. Ellis,
Testing the regional genetic representativeness of captive koala populations
in South-East Queensland, Wildlife
Research, 41, 4,
(277), (2014).Crossref
Karen
H. Black, Gilbert J. Price, Michael Archer and Suzanne
J. Hand, Bearing up well? Understanding the past, present and
future of Australia's koalas, Gondwana
Research, 25, 3,
(1186), (2014).Crossref
Antonios
Augustinos, Kostas Sotirakis, Panayiotis Trigas, Eleftherios
Kalpoutzakis and Vassilis Papasotiropoulos,
Genetic Variation in Three Closely Related Minuartia (Caryophyllaceae) Species
Endemic to Greece: Implications for Conservation Management,
Folia Geobotanica,
49, 4,
(603), (2014).Crossref
KRISTEN
E. LEE, WILLIAM A. H. ELLIS, FRANK N. CARRICK, SEAN
W. CORLEY, STEPHEN D. JOHNSTON, PETER R. BAVERSTOCK, CATHERINE
J. NOCK, KEVIN C. ROWE and JENNIFER
M. SEDDON, Anthropogenic changes to the landscape resulted in
colonization of koalas in north‐east New South Wales, Australia,
Austral Ecology,
38, 3,
(355-363), (2012).Wiley Online Library
Zhou
Rong, Li Jiaqi, Li
You, Liu Naifa, Fang
Fengjie, Shi Limin and Wang
Ying, Genetic variation in rusty-necklaced partridge (Alectoris
magna) detected by mitochondrial DNA, Biodiversity Science, 20, 4,
(451), (2013).Crossref
M.
C. Avila-Arcos, S. Y. W. Ho, Y. Ishida, N.
Nikolaidis, K. Tsangaras, K.
Honig, R. Medina, M.
Rasmussen, S. L. Fordyce, S.
Calvignac-Spencer, E. Willerslev, M. T. P. Gilbert, K.
M. Helgen, A. L. Roca and A.
D. Greenwood, One Hundred Twenty Years of Koala Retrovirus Evolution
Determined from Museum Skins, Molecular
Biology and Evolution, 30, 2,
(299), (2013).Crossref
Tristan
Lee, Kyall R. Zenger, Robert
L. Close and David N. Phalen,
Genetic analysis reveals a distinct and highly diverse koala (Phascolarctos
cinereus) population in South Gippsland, Victoria, Australia,
Australian Mammalogy,
34, 1,
(68), (2012).Crossref
Gail M. Tucker, I. Delma Clifton and Stephen
C. McKillup, Relationships between morphometric variables and
age for captive individuals may not accurately estimate the age of free-ranging juvenile
koalas (Phascolarctos cinereus), Australian
Journal of Zoology, 60, 3,
(173), (2012).Crossref
Kristen
E. Lee, Jennifer M. Seddon, Stephen Johnston, Sean
I. FitzGibbon, Frank Carrick, Alistair Melzer, Fred
Bercovitch and William Ellis,
Genetic diversity in natural and introduced island populations of koalas in
Queensland, Australian
Journal of Zoology, 10.1071/ZO12075, 60,
5, (303), (2012).Crossref
Margaret
Byrne, Dorothy A. Steane, Leo
Joseph, David K. Yeates, Greg
J. Jordan, Darren Crayn, Ken
Aplin, David J. Cantrill, Lyn
G. Cook, Michael D. Crisp, J.
Scott Keogh, Jane Melville, Craig Moritz, Nicholas
Porch, J. M. Kale Sniderman, Paul Sunnucks and Peter
H. Weston, Decline of a biome: evolution, contraction, fragmentation,
extinction and invasion of the Australian mesic zone biota,
Journal of Biogeography,
38, 9,
(1635-1656), (2011).Wiley Online Library
Mark
D. B. Eldridge, Marsupial Population and Conservation Genetics,
Marsupial Genetics and Genomics, 10.1007/978-90-481-9023-2_22, (461-497),
(2010).Crossref
Tristan
Lee, Kyall R. Zenger, Robert
L. Close, Marilyn Jones and David N. Phalen, Defining spatial
genetic structure and management units for vulnerable koala (Phascolarctos cinereus)
populations in the Sydney region, Australia, Wildlife Research, 10.1071/WR09134, 37, 2,
(156), (2010).Crossref
Kristen
E. Lee, Jennifer M. Seddon, Sean W. Corley, William
A. H. Ellis, Stephen D. Johnston, Deidré L. de Villiers, Harriet
J. Preece and Frank N. Carrick,
Genetic variation and structuring in the threatened koala populations of Southeast
Queensland, Conservation
Genetics, 10.1007/s10592-009-9987-9, 11,
6, (2091-2103), (2009).Crossref
Lu
Dong, Jie Zhang, Yue
Sun, Ying Liu, Yanyun
Zhang and Guangmei Zheng, Phylogeographic
patterns and conservation units of a vulnerable species, Cabot’s tragopan (Tragopan
caboti), endemic to southeast China, Conservation
Genetics, 10.1007/s10592-010-0108-6, 11,
6, (2231-2242), (2010).Crossref
Alexandra
Pavlova, Faith M. Walker, Rodney
van der Ree, Silvana Cesarini and Andrea C. Taylor, Threatened populations
of the Australian squirrel glider (Petaurus norfolcensis) show evidence of evolutionary
distinctiveness on a Late Pleistocene timescale, Conservation Genetics, 10.1007/s10592-010-0125-5, 11, 6,
(2393-2407), (2010).Crossref
T.
Mizuno, A. McKinnon, N.
Ichihara, T. Amasaki, M.
Asari, T. Nishita, M.
Oishi, S. Soeta and H.
Amasaki, Histological Structure and Distribution of Carbonic Anhydrase
Isozymes (CA‐I, II, III and VI) in Major Salivary Glands in Koalas,
"Anatomia, Histologia, Embryologia", 38,
6, (449-454), (2009).Wiley Online
Library
Maria A. Nilsson, The structure of
the Australian and South American marsupial mitochondrial control region, Mitochondrial DNA, 20,
5-6, (126), (2009).Crossref
Romane
Cristescu, Valma Cahill, William
B. Sherwin, Kathrine Handasyde, Kris Carlyon, Desley
Whisson, Catherine A. Herbert, Britt Louise J. Carlsson, Alan
N. Wilton and Des W. Cooper,
Inbreeding and testicular abnormalities in a bottlenecked population of koalas
(Phascolarctos cinereus), Wildlife
Research, 10.1071/WR08010, 36,
4, (299), (2009).Crossref
Peter
Menkhorst, Hunted, marooned, re-introduced, contracepted: a history
of Koala management in Victoria, Too close
for comfort, 10.7882/FS.2008.012, (73-92),
(2015).Crossref
R.
Symula, J.S. Keogh and D.C.
Cannatella, Ancient phylogeographic divergence in southeastern
Australia among populations of the widespread common froglet, Crinia signifera, Molecular Phylogenetics and
Evolution, 47, 2,
(569), (2008).Crossref
Martin
Mendez, H. C. Rosenbaum and P. Bordino, Conservation genetics
of the franciscana dolphin in Northern Argentina: population structure, by-catch impacts,
and management implications, Conservation
Genetics, 10.1007/s10592-007-9354-7, 9,
2, (419-435), (2007).Crossref
Anna
Pauline O. Guia and Takashi Saitoh,
The gap between the concept and definitions in the Evolutionarily Significant
Unit: the need to integrate neutral genetic variation and adaptive variation, Ecological Research, 22,
4, (604-612), (2006).Wiley Online Library
WALTER
DURKA, WIESLAW BABIK, JEAN‐FRANCOIS
DUCROZ, DIETRICH HEIDECKE, FRANK
ROSELL, RAVČIGIJN SAMJAA, ALEXANDER
P. SAVELJEV, ANNEGRET STUBBE, ALIUS ULEVIČIUS and MICHAEL
STUBBE, Mitochondrial phylogeography of the Eurasian beaver Castor
fiber L., Molecular
Ecology, 14, 12,
(3843-3856), (2005).Wiley Online
Library
Jean-Francois Ducroz, Michael
Stubbe, Alexander P. Saveljev, Dietrich Heidecke, Rivčan
Samjaa, Alius Ulevičius, Annegret
Stubbe and Walter Durka, GENETIC
VARIATION AND POPULATION STRUCTURE OF THE EURASIAN BEAVER CASTOR FIBER IN EASTERN
EUROPE AND ASIA, Journal
of Mammalogy, 86, 6,
(1059), (2005).Crossref
S.
H. Garland, The assessment of TGGE for the detection of interspecific
and intergeneric DNA-marker polymorphism within Solanaceae,
Australian Journal of Agricultural Research, 10.1071/AR04141,
56, 3,
(291), (2005).Crossref
Ayesha
M. Seymour, Margaret E. Montgomery, Brian H. Costello, Sonja
Ihle, Greg Johnsson, Barbara
St. John, David Taggart and Bronwyn A. Houlden, High effective
inbreeding coefficients correlate with morphological abnormalities in populations
of South Australian koalas (Phascolarctos cinereus),
Animal Conservation,
4, 3,
(211-219), (2006).Wiley Online Library
E.
V. Fowler, B. A. Houlden, P.
Hoeben and P. Timms, Genetic
diversity and gene flow among southeastern Queensland koalas (Phascolarctos cinereus), Molecular Ecology, 9,
2, (155-164), (2001).Wiley Online
Library
Angela M. Penn, William
B. Sherwin, Greg Gordon, Daniel
Lunney, Alistair Melzer and Robert C. Lacy, Demographic Forecasting
in Koala Conservation, Conservation
Biology, 14, 3,
(629-638), (2001).Wiley Online
Library
L. C. Pope, A.
Estoup and C. Moritz, Phylogeography
and population structure of an ecotonal marsupial, Bettongia tropica, determined using
mtDNA and microsatellites, Molecular
Ecology, 9, 12,
(2041), (2000).Crossref
William
B. Sherwin, Peter Timms, Jonathan
Wilcken and Bronwyn Houlden,
Analysis and Conservation Implications of Koala Genetics,
Conservation Biology,
14, 3,
(639-649), (2001).Wiley Online Library
K.
B. Firestone, M. S. Elphinstone, W. B. Sherwin and B.
A. Houlden, Phylogeographical population structure of tiger quolls
Dasyurus maculatus (Dasyuridae: Marsupialia), an endangered carnivorous marsupial, Molecular Ecology, 8,
10, (1613-1625), (2002).Wiley Online
Library
Shannon
R. Kjeldsen, Herman W. Raadsma, Kellie A. Leigh, Jennifer
R. Tobey, David Phalen, Andrew
Krockenberger, William A. Ellis, Emily Hynes, Damien
P. Higgins and Kyall R. Zenger,
Genomic comparisons reveal biogeographic and anthropogenic impacts in the koala
(Phascolarctos cinereus): a dietary-specialist species distributed across heterogeneous
environments, Heredity, 10.1038/s41437-018-0144-4, (2018).Crossref
if (articleRef) articleRef.style.display = "none";
Caption
if(window._satellite)
_satellite.pageBottom();
var _prum=[['id','59e8fecb3847311aab7b23c6'],['mark','firstbyte',(new Date()).getTime()]];(function()var s=document.getElementsByTagName('script')[0],p=document.createElement('script');p.async='async';p.src='//rum-static.pingdom.net/prum.min.js';s.parentNode.insertBefore(p,s);)();
